Resumen
DoCBox aims to develop a new toolbox of fast and easy-to-implement behavioural, neuroimaging and
neurophysiological assessments to accurately assess and diagnose patients suffering from a disorder
of consciousness (DoC), allowing for a more comprehensive examination and better management of this
vulnerable population. This toolbox will respond to the society needs regarding the evaluation of
patients with DoC as it appropriately responds to the rigid time constraints of clinical settings,
which are one of the biggest limitations for an accurate diagnosis. This project aims to enhance
interdisciplinary research on DoC via an exchange of knowledge and international scientific
cooperation to translate and validate the tools (e.g., behavioral scales, pipelines) that will be
included in this toolbox. This collaboration between the partners underpins the credibility and
feasibility of three research objectives: 1) Provide new bedside assessment tools to refine and
optimize the detection of consciousness signs in post-comatose patients; 2) Tdentify the most
accurate neurophysiological and neuroimaging biomarkers of consciousness states and develop novel
easy-to-use software to implement these analyses in clinical settings; 3) Engage informal and
formal caregivers in the diagnosis of DoC patients. This will ultimately result in guidelines and
policy recommendations for improvement of DoC patients' diagnosis and thus care. The proposed
exchange program aims to bring together a large international and interdisciplinary consortium of
17 partners (EU and non-EU countries) including researchers and other professionals with all
necessary skills, permitting to tackle the challenges faced by professionals when studying and
caring
the intersector and interdisciplinary massive data collected by this consortium, which will
llow a major progress in the understanding of (disorders of) consciousness.
