A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability

Autores UPV
Revista European Journal of Medicinal Chemistry


Oral administration of camptothecin (Cm) derivatives and other antitumoral agents is being actively developed in order to improve the quality of life of patients with cancer. Though several lipophilic derivatives of CPT have shown interesting oral bioavai