Autores UPV
Mira Tomás Juan Miguel,
Díaz Martínez María del Alba,
Alberola Rubio José,
Pilar Alama Faubel,
Gemma Castillon Cortes,
Sergio Caballero Sanz,
García Casado Francisco Javier
Abstract
Assisted reproductive technologies are increasingly common due to the rising maternal age. One potential
cause of embryo implantation failure is altered uterine peristalsis patterns. Intracavitary electrohysterography
(IC-EHG) is a recent technique developed to characterize the electrophysiology of uterine peristalsis
throughout the menstrual cycle. Two primary methodologies are employed for analysis: Contraction Analysis
and Window Analysis. This study aims to examine the relationship between parameters describing the same
characteristics of the signals using contraction and window analysis of 2, 4 and 10 minutes. Peristalsis was
recorded at three different menstrual cycle phases from 10 fertile healthy women. Continuous 10 minutes
recordings free of artifacts were selected. A very strong linear relationship (R2 ¿ 0.95) was found between the
amplitude parameter from contraction (Root Mean Square (RMS)) and window (80th percentile of signal RMS
envelope) analysis. For the spectral parameter (Median Frequency), the relationship was strong (0.59 ¿ R2 ¿
0.75), while for the non-linear parameter (Sample Entropy), it was moderate (0.19 ¿ R2 ¿ 0.29). Strongest
relationships were obtained with 2-minutes windows. The findings suggest that window analysis can
accurately assess contraction intensity and, more moderately its spectral content; but basal segments in
window analysis significantly influence the signal complexity parameter.
